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Literature summary extracted from

  • Mori, M.; Morimoto, H.; Kim, Y.; Ui, H.; Nonaka, K.; Masuma, R.; Sakamoto, K.; Kita, K.; Tomoda, H.; Shiomi, K.; Omura, S.
    Ukulactones A and B, new NADH-fumarate reductase inhibitors produced by Penicillium sp. FKI-3389 (2011), Tetrahedron, 67, 6582-6586.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.6 ukulactone A polyketide isolated from a culture broth of Penicillium sp. FKI-3389, shows potent inhibitory activity Ascaris suum
1.3.1.6 ukulactone B polyketide isolated from a culture broth of Penicillium sp. FKI-3389. Inhibitory activity is 200 times weaker than that of epimer ukulactone A Ascaris suum

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.6 Ascaris suum
-
-
-

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.3.1.6 0.0000024
-
 pH 7.0, 37°C Ascaris suum ukulactone A
1.3.1.6 0.00047
-
 pH 7.0, 37°C Ascaris suum ukulactone B